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Listen to my heart

What is heart valve disease?

Your heart is a vital organ that depends on its 4 valves—the tricuspid, pulmonary, mitral, and aortic valves— to help regulate blood flow throughout the body.
What is heart valve disease

Each valve has thin flaps called leaflets that act as one-way doors, opening and closing with each heartbeat. When your valves are healthy, the leaflets open fully to keep blood flowing smoothly in the right direction and close tightly to prevent blood from flowing backwards.

As you get older, you can develop heart valve disease, where one or more of your valves may stop working properly. This condition makes it harder for your heart to pump blood through your body.

  1. 1
    Mitral valve
  2. 2
    Aortic valve
  3. 3
    Pulmonary valve
  4. 4
    Triscuspid valve

Types of heart valve disease

The 2 most common are valve stenosis and valve regurgitation. Both can be deadly if left untreated.1

Valve stenosis

Valve stenosis occurs when your valve leaflets become stiff or fuse together, preventing the valve from opening fully. When the opening gets smaller, blood flow becomes restricted, which means your heart needs to work harder to pump blood to the rest of your body.

Valve regurgitation

Valve regurgitation, also called “leaky valve,” happens when the valve leaflets do not close properly, causing blood to flow or “leak” backwards. As a result, your heart must work harder to push the blood back out.

Aortic stenosis

Aortic stenosis (AS) stands as the most common heart valve disease globally.2
Aortic stenosis

It is a specific type of aortic valve disease where the leaflets of the aortic valve, which control blood flow from the heart, become stiff and narrowed. This prevents the valve from opening properly, consequently obstructing the flow of blood.

On average, 50% of people will die within 2 years of symptoms starting, if left untreated1

1 in 10 people with heart valve failure may die within 5 weeks without recommended treatment3

5 weeks illustration
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Learn about heart valve disease

Are you or a loved one at risk of heart valve disease? Answer these questions to get a personalized discussion guide to review with your doctor or care team.

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References

  1. Généreux P et al. The Mortality Burden of Untreated Aortic Stenosis. J Am Coll Cardiol. 2023;82(22):2101–2109.
  2. Otto CM et al. 2020 ACC/AHA Guideline for Valvular Heart Disease. J Am Coll Cardiol. 2021;77:e25–e197
  3. Malaisrie SC, McDonald E, Kruse J, et al. Mortality while waiting for aortic valve replacement. Ann Thorac Surg. 2014;98(5):1564-70; discussion 1570-1